Three Examples Of Aroma Chemicals

The following Examples shall deliver to illustrate sure specific embodiments within the scope of aroma chemicals and are not to be construed as limiting the scope thereof. aroma chemicals4,4,6-trimethylbicyclo[4. To a 2-liter 3-necked flask fitted with a mechanical stirrer, more funnel, reflux condenser and drying tube was added 15 g. 39 mole of sodium borohydride and 500 ml. To this solution was slowly added 218.

317 moles of 4,4,6-trimethylbicyclo[4. 0]octane-2-one in 50 ml. Subsequent to 3 hours, about 200 ml. The mix was stirred an more two hour, then about 35 ml. concentrated hydrochloric acid was added.

Subsequent to another two hour of stirring, 400 ml. of toluene and 500 ml. The layers were separated and the organic layer was washed 3 times with 100 ml. The combined h2o layers were extracted with toluene. The toluene layers were combined and dried over potassium carbonate.

The solution was concentrated in vacuo and the residue distilled through a 25 cm. Vigreux--column to yield 215. 5 % yield of 4,4,6-trimethylbicyclo [4. aroma chemicalstricyclo[8. 0 2, 9 ]tetradecane-11-ol.

01 mole regarding the tricyclo ketone in 100 ml. of 2-propanol in a 250 ml. Erlenmeyer flask equipped with magnetic stirring bar was added 0. 015 mole of sodium borohydride. The reaction mix was stirred overnight.

The mix was transferred to a separatory funnel, a little drops of concentrated hydrochloric acid added, and then extracted with 3 100 ml. The combined ether extracts were washed with 3 25 ml. portions of 10% aqueous sodium bicarbonate solution, dried over magnesium sulfate and concentrated in vacuo to yield a clean crystalline solid that was recrystallized from petroleum ether to yield 1. 0058 mole, 58% yield of tricyclo[8. 0 2, 9 ]tetradecane-11-ol.

IR: 3610 cm -1, 3450 cm -1. The characteristic aroma chemicalss of some regarding the compounds regarding the instant invention are as follows:. Compound of Example Aroma chemicals. i camphor, minty, woody, patchouly. II weak to odorless, woody.

IV camphoraceous, musty, sweet. VI sweet, powdery, weak, fairly. While the invention was described herein with regard to sure specific embodiments, it is not so limited. It is to be understood that variations and modifications thereof should be created by those skilled within the art without departing from the soul and scope regarding the invention.